I am an Associate Professor at the University of Amsterdam and co-founder & Chief Science Officer of Calli Labs. My research centers on Learning Dynamics in Computer Vision, with Physical AI as my north star — algorithms that understand cause-and-effect and physical dynamics, enabling robust embodied agents to act safely and reliably.
Awarded the ERC Starting Grant and NWO VIDI Career Grant, I direct the QUVA Lab and POP-AART Lab at UvA. My work on causal representations, world models, and mechanistic interpretability forms the theoretical foundation for the next generation of Physical AI.
The dominant paradigm of modern AI has achieved remarkable things by treating intelligence as a function from observations to outputs, refined through oceans of data. But the physical world is causal. It is dynamic. It resists manipulation, conserves energy, flows according to differential equations older than any neural network. And crucially: it acts back.
"True intelligence requires not just pattern recognition, but an understanding of why things happen, what causes what, and what would happen if."
I believe the next frontier of AI is not wider models but deeper understanding — machines that model cause and effect, that embed governing physical laws into their architecture, that build compressed, interpretable representations of how the world actually works. Algorithms that are not only accurate but controllable, auditable, and safe.
This is Physical AI: not AI applied to physical problems, but AI that is physically grounded — in causality, in mechanism, in the language of dynamics. My research advances this vision through four interlocking programs, each essential to the larger whole:
Learnable digital twins that simulate the world, enabling robots and embodied agents to reason about the consequences of actions before executing them. Our compositional approach achieves remarkable generalization and transferability with scarce real-world data.
Discovering causal structure in visual data through temporal interventions and interaction signals. Our representations identify true cause-and-effect relationships, enabling agents that generalize robustly to unseen scenarios far beyond the training distribution.
Neural networks that incorporate physical governing mechanisms — conservation laws, differential equations, structured priors. Controllable, auditable, interpretable AI systems that are not merely accurate but fundamentally trustworthy.
Applying physics-informed learning to medical imaging and biomedical data — from CT perfusion in acute ischemic stroke to radiation therapy planning for cancer. Algorithms that not only predict but respect the physical laws governing the body.
Long-term research collaborations bridging fundamental AI with industrial-scale deployment.
€1M collaboration on transferring world models research to real-world robot learning systems. Joint work on compositional scene understanding and generalizable manipulation.
Ongoing research dialogue on foundation models and the future of general-purpose world models. Invited speaker at NXAI@NeurIPS on world models and Physical AI.
Joint research laboratory at the University of Amsterdam exploring efficient, scalable AI for computer vision and embodied intelligence. Co-supervising 3 PhD students.
AI-driven radiation therapy optimisation and oncological imaging. Joint research lab with NKI, co-supervising 3 PhD students on physics-informed learning for cancer treatment.
Spun out of the University of Amsterdam and Gunpowder Sky (leading Hollywood production studio). Building AI for augmenting creativity — transforming how artists, creators, and filmmakers collaborate with machine intelligence.
Focus: Video understanding, world models, creative AI applications
Visit Calli Labs →Advisor in NWO Round Table CS — Selected as advisor to the Netherlands Organisation for Scientific Research strategic advisory board for Computer Science.
Member of IPN Network — Joined the IPN (ICT Research Netherlands) network, collaborating on national AI and computing research initiatives.
Summit with 10+ leading European robotics industries to discuss the future of Physical AI and possible collaborations.
Calli Labs co-founded — AI for augmenting creativity, spun out of UvA and Gunpowder Sky (Hollywood production studio).
Greeks in AI Symposium 2025 — 500+ participants. Founded and chaired the inaugural event connecting Greek AI researchers across academia and industry.
ELLIOT Consortium granted €30M (HORIZON-CL4-2024) — pan-European initiative on open multimodal foundation models.
Best Paper Runner-Up at MIDL 2024 for physics-informed neural fields for CT perfusion analysis in acute ischemic stroke.
PhD cum laude awarded to Phillip Lippe — a rare distinction at the University of Amsterdam — for pioneering causal representations in embodied AI.
Elected Programme Director of the BSc AI at the University of Amsterdam. Mission: modernise the curriculum for the Physical AI era.